Purisys has been acquired by the Siegfried Group and continues to provide all existing services as part of the Siegfried Acceleration Hub, including preclinical, early-phase development and manufacturing, reference standards and small-scale GMP manufacturing for commercial APIs.
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Siegfried Acceleration Hub

Maximizing speed to market with early-phase development and manufacturing based in the United States.

Your partner for early-phase development and manufacturing

The Siegfried Acceleration Hub, now also including Purisys, is your comprehensive partner for preclinical and early-phase drug development and manufacturing. From phase-appropriate analytical and validation method development to scalable manufacturing processes, we provide the capabilities and support needed to accelerate your path from concept to clinic. 

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Accelerating early-phase drug development 

We provide seamless support from preclinical through early phases to commercial manufacturing, including scale-up, technology transfer, validation, and product launch. Supported by DMFs across the U.S., Canada, Japan, and the EU. 

 

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Based in the
United States

 Our local presence enables real-time collaboration, reducing delays and enabling efficient scale-up. We ensure regulatory compliance, transparency, and faster development by eliminating offshore transfer risks.  

 

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Seamless transfer into Siegfried's network

 Smooth transition into Siegfried’s global manufacturing network from early phase through to commercial production, all from a single partner 

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Decades of
experience

An agile team with extensive experience in accelerating drug development through early phases, backed by Siegfried's 150 years of development expertise. 

Our services

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Early-phase development and manufacturing

Our CDMO services for early-phase development and manufacturing support your program from pre-clinical to clinical supply, with seamless transfer into commercial production. 

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Comprehensive reference standards offering

We offer a leading catalogue of over 300 reference standards, supported by structural elucidation, full characterization data, and rapid development capabilities for regulatory and commercial needs. 

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Small-scale GMP manufacturing for commercial APIs

Small-scale GMP manufacturing with high-containment capabilities for commercial production of specialized APIs, including low bioburden products for parenteral applications. 

Our technologies and capabilities

Route scouting
Alternate synthesis
Phase-appropriate preclinical process development
Highly potent API's
Registration campaigns
Process validation campaigns
Analytical chromatography method development and validation
Life-cycle project / product management
Advanced filtration technologies
Controlled substances
CMC sections of DMFs
OPEX process optimization
Spray drying

Insights from our experts

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Three success factors to accelerate your program to clinical trial

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Ask better, move faster: Questions that will accelerate the speed of your program to clinical

Subscribe now to get more expert insights

 

Our locations
 

Acceleration Hub Athens, Georgia

The Siegfried Acceleration Hub Athens (formerly Purisys) specializes in pre-clinical and early-phase development and manufacturing. Established in 1982, the site serves both emerging biotech and established pharmaceutical companies, offering high-quality custom synthesis, process development, scale-up, and GMP manufacturing services.


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Acceleration Hub Grafton, Wisconsin

The Siegfried Acceleration Hub Grafton specializes in early-phase development and manufacturing. Established in 1998, the site serves both emerging biotech and established pharmaceutical companies, offering high-quality custom synthesis, process development, scale-up, and GMP manufacturing services. Its capabilities include the handling of highly potent APIs and controlled substances.

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Get in touch

Contact us to discuss your preclinical and early-phase development and manufacturing needs.