What are you
looking for?
Siegfried provides reliable and flexible fill-finish solutions for prefilled syringes and cartridges. Combining proven aseptic manufacturing expertise, advanced fill-finish technologies and an agile, customer-centric approach, we help our partners navigate changing requirements and bring therapies to patients with confidence.
Your project is supported by a dedicated team that understands your product and priorities. With an agile, customer-centric approach, flexible manufacturing solutions and extensive experience in technology transfers, including vial-to-PFS, we tailor our services to your specific needs and support your growth.
Built on decades of aseptic manufacturing experience, we support both biologics and small molecules with the highest standards of quality, regulatory compliance and operational reliability, continuously improving our processes to maintain excellence and meet evolving regulatory requirements.
With manufacturing capabilities in both Europe and the United States, we help our customers build resilient supply chains through flexible second-source and dual-source strategies.
From sensitive biologics to small molecules, our advanced capabilities support product quality, manufacturing flexibility and regulatory compliance.
Low-shear filling systems to minimize mechanical harm to complex biologics. Minimized time of refrigeration to handle temperature-sensitive actives safely. Inert atmosphere processing (Argon/N₂) to combat oxygen sensitivity
Advanced isolator technology meeting strict quality expectations incl. FDA, EMEA and ANVISA. Dual visual inspections incorporating automated or manual checkpoints.100% in-line weighing, dose and re-dose-in control systems to minimize product loss
Small- and medium-scale batch sizes with capacities from 2500 units of up to 100,000 units in 48 hours. Single-use setups to eliminate cross-contamination risks and speed up changeovers. Automated stopper replenishment to minimize human intervention
Full Annex 1 compliance and alignment with FDA and EMA requirements, providing security against evolving regulations. Inspection-ready manufacturing supporting long-term compliance. Comprehensive contamination control strategies designed to safeguard product quality and patient safety
As a trusted partner for sterile injectable manufacturing, Siegfried combines technical expertise, operational flexibility, and a strong commitment to quality. Our dedicated teams work closely with customers to support successful product development, transfer, and commercial supply.