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From clinical supply to commercial manufacturing, Siegfried supports pharmaceutical and biotech companies with reliable prefilled syringe solutions. Combining proven aseptic manufacturing expertise, advanced fill-finish technologies and dedicated project teams, we help bring innovative therapies to patients with confidence.
Your project is supported by a dedicated team that understands your product and priorities. With an agile, customer-centric approach, we adapt to changing requirements and support your growth from development to commercial supply.
Built on decades of aseptic manufacturing experience, we support both biologics and small molecules with the highest standards of quality, regulatory compliance, and operational reliability.
With manufacturing capabilities in both Europe and the United States, we help our customers build resilient supply chains through flexible second-source and dual-source strategies.
From sensitive biologics to small molecules, our advanced capabilities support product quality, manufacturing flexibility and regulatory compliance.
Low-shear filling systems to minimize mechanical harm to complex biologics Temperature control during filling to handle sensitive actives safely. Inert atmosphere processing (Argon/N₂) to combat oxygen sensitivity
Advanced isolator technology meeting strict FDA hygiene expectations Dual visual inspections incorporating both automated and manual checkpoints.100% in-line weighing, dose and re-dose-in control systems to minimize product loss
Small- and medium-scale batch sizes, with capacities of up to 100,000 units in 48 hours. Single-use setups to eliminate cross-contamination risks and speed up changeovers. Automated stopper replenishment to drastically minimize human intervention
Full Annex 1 compliance and alignment with FDA and EMA requirements, providing security against evolving regulations. Strong CMC supply support helping small-to-mid scale companies navigate tech transfers. Comprehensive contamination control strategies designed to safeguard product quality and patient safety
As a trusted partner for sterile injectable manufacturing, Siegfried combines technical expertise, operational flexibility, and a strong commitment to quality. Our dedicated teams work closely with customers to support successful product development, transfer, and commercial supply.